A REVIEW OF NR1-SITE.COM

Employing this solution, Kalbaugh et al. assigned affinity and efficacy roles to positions from the LBDs on the NR1 and NR2A NMDAR subunits. In situ mutation of residues in direct connection with sure ligand afflicted both efficacy and affinity, even though positions that stabilize the shut cleft conformation without having a direct ligand interact